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This digital document is a journal article from Analytica Chimica Acta, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.Description: A near infrared spectroscopic (NIRS) method is established for quantitative determination of naphthodianthrones and phloroglucine derivatives in St. John's Wort extracts. The validated NIRS method is compared with optimised liquid chromatography (LC) and capillary electrophoresis (CE), applying UV as a detection tool. Optimisation of stationary and mobile phase conditions in reversed-phase liquid chromatography (RP-LC) allow separating the derivatives of interest with high peak symmetry and robustness. Elution takes 15 and 25min on non-porous or porous silica C18 with different porosities, respectively. Capillary electrophoresis (CE) is used for cross-validation of RP-LC. CE enables baseline separation of hypericine and pseudohypericine in less than 2min, but is ten times less sensitive. The validated RP-LC is chosen as a reference method for calibration of the NIRS-system. Analysis of 80 St. John's Wort extracts (320 NIR spectra) and the subsequent chemometric calculations of the best regression model show that NIRS is suitable for analysis of hypericine, pseudohypericine and hyperforine. RP-LC or CE must be employed for the other remaining lower concentrated naphthodianthrone and phloroglucine derivatives. Hypericine and hyperforine are analysed via NIRS with a standard error of estimation (SEE) of 0.52 and 0.50@mgmL^-^1 and standard error of prediction (SEP) of 0.64 and 0.71@mgmL^-^1 within few seconds. The current study demonstrates the suitability of NIRS as an alternative to LC and CE for St. John's Wort producing phytopharmaceutical industry. The short analysis time of few seconds' assures high sample throughput in routine analysis.

This digital document is a journal article from Developmental Review, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.Description: Massage therapy has been notably effective in preventing prematurity, enhancing growth of infants, increasing attentiveness, decreasing depression and aggression, alleviating motor problems, reducing pain, and enhancing immune function. This review covers massage therapy research from the last decade, as an update to the American Psychologist 1998 review paper. Models are presented for potential biochemical and physiological mechanisms underlying the massage therapy effects.

This digital document is a journal article from Comparative Biochemistry and Physiology, Part C, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.Description: We compared the therapeutic efficacy of captopril and a thiol chelating agent, meso 2,3-dimercaptosuccinic acid (DMSA) either individually or in combination against arsenite induced oxidative stress and mobilization of metal in rats. Animals were exposed to 100 ppm arsenite as sodium arsenite in drinking water for six weeks followed by treatment with DMSA (50 mg/kg, orally), captopril (50 mg/kg, intraperitoneally) either alone or in combination, once daily for 5 consecutive days. Arsenite exposure led to a significant depletion of blood @d-aminolevulinic acid dehydratase (ALAD) activity, glutathione and platelet levels while significantly increased the level of reactive oxygen species (in RBCs). Hepatic reduced glutathione (GSH) level showed a significant decrease while, thiobarbituric acid reactive substances (TBARS) levels increased on arsenite exposure indicating arsenite induced hepatic oxidative stress. Kidney GSH, GSSG, catalase and TBARS remained unchanged on arsenite exposure. Treatment with DMSA was effective in increasing ALAD activity while, captopril was ineffective when given alone. Captopril when co-administered with DMSA also provided no additional beneficial effect on blood ALAD activity but significant brought altered platelet counts back to the normal value. In contrast, administration of captopril alone provided significant beneficial effects on hepatic oxidative stress, and in combination with DMSA provided a more pronounced recovery in the TBARS level compared to the individual effect of DMSA and captopril. Renal biochemical variables remained insensitive to arsenite and any of the treatments. Interestingly, combined administration of captopril with DMSA had a remarkable effect in depleting total arsenic concentration from blood and soft tissues. These results lead us to conclude that captopril administration during chelation treatment had some beneficial effects particularly on the protection of inhibited blood ALAD activity, and depletion of arsenic level. The study supports our earlier conclusion that a co-administration of an antioxidant is more beneficial than monotherapy with the chelating agents, in

Train harder, recover quickly, and improve performance! Todays top athletes rely on sport massage to stay healthy, at the top of their game, and a step ahead of the competition. With Massage for Sport Performance, you can too. In this special book and DVD package, renowned sport massage therapist Michael McGillicuddy demonstrates the same techniques he has used to train and prepare the worlds elite track and field athletes for Olympic competition. Massage for Sport Performance will show you how to perform both self-massage and partner-assisted massage; administer the most effective routines for pre- and postcompetition; stretch, warm up, and activate primary muscles; treat critical muscle groups for elevated performance; speed recovery; and minimize injury, pain, and fatigue. Throughout youll also find advice, tips, and variations for specific sports as well as massage recommendations for basketball, running, track and field, soccer, and swimming. With step-by-step instruction, photo sequences, and video demonstrations of the primary techniques, Massage for Sport Performance is the definitive guide for players, coaches, and athletes alike.

More than 60 million books sold in the Teach Yourself series!Learn to use Ayurveda for a more balanced, natural way of life Boost Your Vitality with Ayurveda is a comprehensive guide to this ancient healing Indian tradition. You will understand exactly what your type is before getting expert physical and mental advice on the lifestyle and diet that will work for you. Theres also a complete list of effective home remedies for minor ailments. Features: Practical advice on diet and exercise and spiritual inspiration for living in harmony with nature One, five and ten-minute introductions to key principles to get you started Lots of instant help with common problems and quick tips for success, based on the authors' many years of experience Tests in the book and online to keep track of your progress Quick refreshers to help you remember the key facts

Live a life of peace, love, and happiness through spiritual awakening In Wake Up Now, author Stephan Bodian--nationally recognized expert on meditation and spirituality and former editor-in-chief of Yoga Journal--reveals that spiritual awakening is not some faraway dream, or overly complicated to achieve, but an ever-present reality that is always available here and now. Based on his own experience and over 30 years of teaching the direct approach to spiritual awakening, Bodian has broken down the awakening process into five overlapping, loosely sequential stages: seeking, awakening, deepening and clarifying, embodying, and living the awakened life. Wake Up Now guides you through every stage of the journey, from the process of seeking through the often prolonged and challenging process of integrating the awakening into everyday life. "This book is one of the most concise guides to spiritual awakening I have read. Both profound and practical, it guides the reader through the intricacies of awakening as only someone who has walked the walk themselves can do. The clarity and compassion this book offers the sincere spiritual seeker is both rare and welcome."--Adyashanti, renowned spiritual teacher and author of The Impact of Awakening and Emptiness Dancing Topics include: Entering the Gateless Gate; Seeking without a Seeker; Freedom from the Known; The Practice of Presence; Who is Experiencing this Moment Right now; Spontaneous Awakening; In the Wake of Awakening; Embodying the Light; Freeing the Dark Inside the Light; The Awakened Life

Get in touch with your feet and improve your overall health Get Started in Reflexology contains spiritual insight into the links between mind and body, especially when it comes to the feet. This book explains the background and context of reflexology, the link between thought, well-being, and feet. It gives you immediate and proven, easy-to-follow techniques for foot massage and shows how reflexology can help with common ailments. You can also visit teachyourself.com for extension articles and a vibrant community of like-minded learners. And if you don't have much time, don't worry--this book gives you one-, five-, and 10-minute bites of learning to get you started.

A debilitating disease of pain, inflammation, loss of mobility, and loss of quality of life, arthritis takes victims of all ages, from young children to seniors. Usually chronic, the broad term arthritis refers to nearly 100 distinct manifestations each with their own etiology, pathophysiology, and treatment. With medical research getting so much attention it is no wonder there have been recent leaps in the investigation into arthritis treatment. It is important to have a high quality, trusted compendium to capture the breadth and depth of new information in the field. Covering cutting-edge information on arthritic diseases and their treatment, Arthritis: Pathophysiology, Prevention, and Therapeutics details the intricacies of arthritis and inflammatory responses, their consequences, their economic burden, and their impact on society.

Too often in biostatistical research and clinical trials, a knowledge gap exists between developed statistical methods and the applications of these methods. Filling this gap, Clinical Trial Data Analysis Using R provides a thorough presentation of biostatistical analyses of clinical trial data and shows step by step how to implement the statistical methods using R. The books practical, detailed approach draws on the authors 30 years of real-world experience in biostatistical research and clinical development. Each chapter presents examples of clinical trials based on the authors actual experiences in clinical drug development. Various biostatistical methods for analyzing the data are then identified. The authors develop analysis code step by step using appropriate R packages and functions. This approach enables readers to gain an understanding of the analysis methods and R implementation so that they can use R to analyze their own clinical trial data. With step-by-step illustrations of R implementations, this book shows how to easily use R to simulate and analyze data from a clinical trial. It describes numerous up-to-date statistical methods and offers sound guidance on the processes involved in clinical trials.

Now in paperback, the bestselling exploration of the effects of the mind-body connection on stress and diseaseCan a person literally die of loneliness Is there such a thing as a "cancer personality" Drawing on scientific research and the author's decades of experience as a practicing physician, this book provides answers to these and other important questions about the effect of the mind-body link on illness and health and the role that stress and one's individual emotional makeup play in an array of common diseases.Explores the role of the mind-body link in conditions and diseases such as arthritis, cancer, diabetes, heart disease, IBS, and multiple sclerosisDraws on medical research and the author's clinical experience as a family physicianIncludes The Seven A's of Healing-principles of healing and the prevention of illness from hidden stressShares dozens of enlightening case studies and stories, including those of people such as Lou Gehrig (ALS), Betty Ford (breast cancer), Ronald Reagan (Alzheimer's), Gilda Radner (ovarian cancer), and Lance Armstrong (testicular cancer)An international bestseller translated into fifteen languages, When the Body Says No promotes learning and healing, providing transformative insights into how disease can be the body's way of saying no to what the mind cannot or will not acknowledge.